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Objectives
Systemic Onset Juvenile Idiopathic/Rheumatoid Arthritis
Systemic Onset Juvenile Idiopathic Arthritis: Epidemiology
Systemic Onset Juvenile Idiopathic Arthritis: Manifestations
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Systemic Onset Juvenile Idiopathic Arthritis: Manifestations
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Systemic Onset Juvenile Idiopathic Arthritis: Manifestations
Systemic Onset Juvenile Idiopathic Arthritis: Manifestations
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Systemic Onset Juvenile Idiopathic Arthritis: Growth Suppression
Systemic Onset Juvenile Idiopathic Arthritis: Arthritis
Systemic Onset Juvenile Idiopathic Arthritis: Rare Manifestations
Systemic Onset Juvenile Idiopathic Arthritis: Laboratory
Systemic Onset Juvenile Idiopathic Arthritis: Radiographic Features
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Is Systemic Juvenile Rheumatoid Arthritis an Interleukin 6 Mediated Disease?
Systemic Onset Juvenile Idiopathic Arthritis: IL-6 Overproduction
Is Systemic Juvenile Rheumatoid Arthritis an Interleukin 6 Mediated Disease?
-174G Allele of the IL-6 Gene Confers Susceptibility to SoJIA
-173 Polymorphism of the Macrophage Migration Inhibitory Factor Gene in SoJIA
-173 Polymorphism of the Macrophage Migration Inhibitory Factor Gene in SoJIA
Systemic Onset Juvenile Idiopathic Arthritis: Treatment
Humanized anti-IL-6 receptor monoclonal antibody (MRA):
Systemic Onset Juvenile Idiopathic Arthritis: Prognosis
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3 yof with devastating disease: fever, polyarthritis, and rash
Systemic Onset Juvenile Rheumatoid Arthritis and Macrophage Activation Syndrome
SoJRA and Macrophage Activation Syndrome (MAS)
Macrophage Activation Syndrome
MAS: clinical features
MAS: laboratory features
MAS: laboratory features
MAS triggers
MAS: Bone Marrow Biopsy
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MAS: Diagnosis
MAS: Diagnosis
Coagulopathy in MAS
MAS and HLH
MAS and Hemophagocytic Lymphohistiocytosis
Diagnostic guidelines for Hemophagocytic Lymphohistiocytosis
MAS: epidemiology
HLH/MAS: pathophysiology
Immunologic Abnormalities in FHLH
Perforin
Immunologic abnormalities in MAS/soJRA are similar to HLH
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MAS and soJRA
NK/perforin and cellular immune responses
NK/perforin and cellular immune responses
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Chart
MAS: treatment
MAS: outcome
MAS

Murray Passo, M.D., Alexei Grom, M.D.

Systemic Onset Juvenile Rheumatoid Arthritis and Macrophage Activation Syndrome