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Acute Rheumatic Fever and Post-Streptococcal Arthritis:
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Epidemiology
Epidemiology
Rheumatic Fever Jones Criteria
Rheumatic Fever Jones Criteria
Jones Criteria
Rheumatic Fever Jones Criteria
Additional Manifestations
Carditis
Aschoff body
Arthritis
Arthritis
Arthritis
Migratory Arthritis
Polyarthritis
Chorea
Chorea
Erythema marginatum
Erythema marginatum
Subcutaneous nodules
Subcutaneous nodules
Evaluating antecedent streptococcal infection
Role of the streptococcus
Evaluating antecedent streptococcal infection
Evaluating antecedent streptococcal infection
Evaluating antecedent streptococcal infection
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Evaluating antecedent streptococcal infection
Evaluating antecedent streptococcal infection
Evaluating antecedent streptococcal infection
CHF in Rheumatic Carditis
Post-streptococcal reactive arthritis (PSRA)
Dilemmas in PSRA
PSRA vs ARF: Clinical manifestations
PSRA vs ARF: Clinical manifestations
PSRA vs ARF: Extra-articular manifestations
Carditis after PSRA
Carditis after PSRA
Carditis after PSRA
Carditis after PSRA
Monoarthritis vs. Polyarthritis
Carditis in Subsequent Episodes
Proposed Criteria for PSRA
Proposed Criteria for PSRA
Proposed Prophylaxis Regimen in PSRA
Guidelines for obtaining streptococcal serology
Prevalence of Elevated Antistreptococcal Antibody Titers
Conclusions in PSRA
Question in PSRA
Factors in Pathogenesis
Pathogenesis
Pathogenesis
B cell alloantigen D8/17
B cell alloantigen D8/17
B cell alloantigen D8/17
HLA typing in PSRA
Characteristics of streptococcus
Treatment
NSAIDDs vs. Aspirin
NSAIDDs vs. ASA
NSAIDDs vs. ASA
Treatment
Questions for the future
Future Directions
Q & A

T. Brent Graham, MD

"Acute Rheumatic Fever and Post-streptococcal Arthritis: Clinical Dilemmas" - Pediatric Grand Rounds - 12/3/02